Click on image to view larger version.
Fig. 1. Substance with properties of lipofuscin, prepared by UV cross-linking of mouse liver mitochondria. The pellet in the tube on the right was obtained from homogenized tissue prior to cross-linking; the pellet on the left was from cross-linked material. In the lower panel, the tubes were illuminated under fluorescent light using a filter cube designed for the detection of fluorescein isothiocyanate. [Fluorescence of the cross-linked material was also evident using 4',6-diamidino-2-phenylindole-2HCl (DAPI) or Cy3 filter cubes.]
[PowerPoint download feature is available to paid individual subscribers and to registered users at subscribing institutions (register for free).]
You may download the image(s) above for non-profit educational presentation use only, provided no modifications are made to the content. Any use, publication, or distribution of the image(s) beyond that permitted in the sentence above or beyond that allowed by the "Fair Use" limitations (sections 107 and 108) of the US Copyright law requires the prior written permission of AAAS. This permission does not apply to images that are credited to non-AAAS sources. For images credited to non-AAAS entities, you will need to obtain permission from the entity listed in the legend or credit line before making any use of the image(s).