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Fig. 1. Substance with properties of lipofuscin, prepared by UV cross-linking of mouse liver mitochondria. The pellet in the tube on the right was obtained from homogenized tissue prior to cross-linking; the pellet on the left was from cross-linked material. In the lower panel, the tubes were illuminated under fluorescent light using a filter cube designed for the detection of fluorescein isothiocyanate. [Fluorescence of the cross-linked material was also evident using 4',6-diamidino-2-phenylindole-2HCl (DAPI) or Cy3 filter cubes.]

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