Sci. Aging Knowl. Environ., 3 October 2001
Vol. 2001, Issue 1, p. dn2
[DOI: 10.1126/sageke.2001.1.dn2]

NEURODEGENERATIVE DISEASE CASE STUDIES

Alzheimer's Disease

Lawrence S. Honig, and Steven S. Chin

The authors are at Columbia University College of Physicians and Surgeons, in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, The Alzheimer's Disease Research Center, the Sergievsky Center, and the Department of Neurology, and the Department of Pathology, New York, NY 10032, USA. E-mail: lh456{at}columbia.edu (L.H.)

http://sageke.sciencemag.org/cgi/content/full/sageke;2001/1/dn2

Abstract: In this case study, we describe the symptoms, neuropsychological testing, and brain pathology of a man with Alzheimer's disease (AD). AD commonly presents with impairment of memory and language function. In this case, language difficulties were noted more prominently than was memory impairment. Throughout the limbic system and neocortex of the patient were large numbers of senile plaques and neurofibrillary tangles, the pathological hallmarks of AD.

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