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Sci. Aging Knowl. Environ., 3 October 2001
Vol. 2001, Issue 1, p. oa2
[DOI: 10.1126/sageke.2001.1.oa2]

HOT TOPIC ORIENTATIONS

Detangling Alzheimer's Disease

New insights into the biological bases of the most common cause of dementia are pointing to better diagnostics and possible therapeutics

Laura Helmuth

http://sageke.sciencemag.org/cgi/content/full/sageke;2001/1/oa2

Abstract: Alzheimer's disease (AD) afflicts 4 million people in the United States and is expected to strike 14 million by the year 2050, as the population ages. Researchers are scrambling to find genetic risk factors, decipher disease mechanisms, and develop reliable diagnostic tests that detect the illness at its earliest, potentially most treatable stage. Using these findings, they hope to devise new therapeutic approaches. Current clinical trials are testing novel techniques that stall or reverse AD-like neuropathology in mice.

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Science of Aging Knowledge Environment. ISSN 1539-6150