Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Sci. Aging Knowl. Environ., 3 October 2001
Vol. 2001, Issue 1, p. oa5
[DOI: 10.1126/sageke.2001.1.oa5]

HOT TOPIC ORIENTATIONS

The Two Faces of Oxygen

The byproducts of aerobic metabolism might promote aging--and normal cellular processes

Rabiya Tuma

http://sageke.sciencemag.org/cgi/content/full/sageke;2001/1/oa5

Abstract: Scientists have suspected for half a century that reactive oxygen species (ROS) are major instigators of aging. These byproducts of metabolism batter a wide variety of molecules within cells, and an organism's ability to repair the damage declines with age. Now, some researchers say they're wrapping up the case against ROS, at least for lower organisms. By counteracting this destruction with protective enzymes, researchers have extended the average lifetime of some invertebrates. But the verdict isn't in yet, because recent studies have revealed that ROS also make key contributions to normal cell signaling.

Read the Full Text

To Advertise     Find Products

Science of Aging Knowledge Environment. ISSN 1539-6150