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Sci. Aging Knowl. Environ., 9 January 2002
Vol. 2002, Issue 1, p. nf1
[DOI: 10.1126/sageke.2002.1.nf1]

NEWS FOCUS

Eschew Beaucoup Q

Katharine Miller

http://sageke.sciencemag.org/cgi/content/full/sageke;2002/1/nf1

Abstract: Everything that once used oxygen to produce energy contains a multipurpose lipid called ubiquinone or coenzyme Q, but Q-loaded meals might be more curse than blessing: Adult roundworms live longer without dietary Q, according to new research. Because coenzyme Q can foster the production of reactive oxygen species (ROS), molecular mischief-makers that damage a wide range of cellular molecules, the results might support the view that ROS promote an animal's demise. The work, published in the 4 January issue of Science (p. 120), also contributes to the notion that aging results from the activity of genes that benefit an animal early in life--so that it reaches reproductive maturity--but harm it later.

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