Sci. Aging Knowl. Environ., 10 April 2002
An Untwister's New Twist
R. John Davenporthttp://sageke.sciencemag.org/cgi/content/full/sageke;2002/14/nf6
Abstract: Defects in helicase enzymes result in a number of diseases that mimic aspects of growing old. New work shows that a helicase implicated in one of these conditions--xeroderma pigmentosum (XP)--apparently helps hormones activate genes in addition to its well-known ability to unwind DNA. The protein's newly discovered role in hormone signaling might underlie unexplained XP symptoms.
Science of Aging Knowledge Environment. ISSN 1539-6150