Sci. Aging Knowl. Environ., 29 May 2002
Vol. 2002, Issue 21, p. pe7
[DOI: 10.1126/sageke.2002.21.pe7]


The Naked Mole Rat--A New Record for the Oldest Living Rodent

Rochelle Buffenstein, and Jennifer U. M. Jarvis

R. Buffenstein is in the Department of Biology at the City College of the City University of New York, New York, NY 10031, USA. J. U. M. Jarvis is in the Department of Zoology at the University of Cape Town, Private Bag, Rondebosch, Cape Town, 7700 South Africa. E-mail: rbuffen{at} (R.B.);2002/21/pe7

Key Words: naked mole rat • longevity record • rodent longevity • theories of aging

Abstract: We report a new record for the world's longest-lived rodent, a male naked mole rat (Heterocephalus glaber). On the basis of his weight at capture, this animal was approximately 1 year old when collected near Mtito Andei, Kenya in July/August 1974. He died in April 2002, indicating that he lived for more than 28 years. As such, his life-span surpassed the previous longevity record for a rodent, which was held by a porcupine (Hystrix brachyura) that lived for 27 years and 4 months.

Read the Full Text

Naked mole-rat transcriptome signatures of socially-suppressed sexual maturation and links of reproduction to aging.
M. Bens, K. Szafranski, S. Holtze, A. Sahm, M. Groth, H. A. Kestler, T. B. Hildebrandt, and M. Platzer (2019)
   Abstract »    Full Text »    PDF »
Matrilineal Transmission of Familial Excess Longevity (mtFEL): Effects on Cause-specific Mortality in Utah, 1904 - 2002.
E. OBrien, R. M. Cawthon, K. R. Smith, and R. A. Kerber (2019)
   Abstract »    Full Text »    PDF »
Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat.
A. Seluanov, C. Hine, J. Azpurua, M. Feigenson, M. Bozzella, Z. Mao, K. C. Catania, and V. Gorbunova (2009)
PNAS 106, 19352-19357
   Abstract »    Full Text »    PDF »
How to learn new and interesting things from model systems based on "exotic" biological species.
J. M. Sedivy (2009)
PNAS 106, 19207-19208
   Full Text »    PDF »
Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.
V. I. Perez, R. Buffenstein, V. Masamsetti, S. Leonard, A. B. Salmon, J. Mele, B. Andziak, T. Yang, Y. Edrey, B. Friguet, et al. (2009)
PNAS 106, 3059-3064
   Abstract »    Full Text »    PDF »

Science of Aging Knowledge Environment. ISSN 1539-6150