Sci. Aging Knowl. Environ., 17 July 2002
High-Octane Endurance--Yeast in the Metabolic Fast Lane Live Longer
Abstract: Yeast don't shoot craps or snort cocaine, but a different kind of fast life might invigorate them, according to new research. Many scientists have wondered whether slowing metabolism could prolong life. The findings suggest instead that speeding it up might do the trick, at least in yeast. They also tie together the effects of known life extenders, showing that calorie restriction harnesses a protein that governs aging, Sir2p. Although many questions remain about how faithfully the results will transfer to mammals, the work challenges some old ideas and hints that researchers should look at the relation between metabolism and longevity in a new way.
Citation: E. Strauss, High-Octane Endurance--Yeast in the Metabolic Fast Lane Live Longer. Science's SAGE KE (17 July 2002), http://sageke.sciencemag.org/cgi/content/full/sageke;2002/28/nf9
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