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Sci. Aging Knowl. Environ., 20 November 2002 NEWS FOCUSHaving It All After Allp53 surplus staves off cancer but doesn't speed agingR. John Davenport http://sageke.sciencemag.org/cgi/content/full/sageke;2002/46/nf13Abstract: Bumping up amounts of the antitumor protein p53 protects mice against cancer, but it also accelerates aging. Now scientists reveal that beefing up the p53 force in a controlled manner can thwart cancer without speeding the animals' demise. Additional work is needed to verify that the mice don't age more rapidly than normal and that p53--and not another gene--underlies the effect. Citation: R. J. Davenport, Having It All After All. Science's SAGE KE (20 November 2002), http://sageke.sciencemag.org/cgi/content/full/sageke;2002/46/nf13
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