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Sci. Aging Knowl. Environ., 8 January 2003
Vol. 2003, Issue 1, p. vp1
[DOI: 10.1126/sageke.2003.1.vp1]


An Engineer's Approach to the Development of Real Anti-Aging Medicine

Aubrey D. N. J. de Grey

The author is in the Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK. E-mail: ag24{at};2003/1/vp1

Key Words: mammalian aging • mutations • aggregates • cross-links • cell senescence • cell loss • life extension

Abstract: In this Viewpoint, I list the various age-related molecular and cellular changes that are thought to limit mammalian life-span, and I outline a problem-solving approach to reversing these detrimental changes. This approach should help to prevent the development of these age-related changes into life-threatening pathologies and possibly, in due course, allow a large increase in healthy human life expectancy.

Citation: A. D. N. J. de Grey, An Engineer's Approach to the Development of Real Anti-Aging Medicine. Sci. SAGE KE 2003, vp1 (8 January 2003);2003/1/vp1

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Science of Aging Knowledge Environment. ISSN 1539-6150