Sci. Aging Knowl. Environ., 26 March 2003
Vol. 2003, Issue 12, p. vp2
[DOI: 10.1126/sageke.2003.12.vp2]

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Help Available--Phenomenological Models for Research on Aging

Arnold Mitnitski, and Kenneth Rockwood

Arnold Mitnitski is in the Departments of Medicine and Computer Science, and Kenneth Rockwood is in the Department of Medicine (Geriatric Medicine & Neurology), Dalhousie University, Halifax, Nova Scotia, Canada. E-mail: Arnold.Mitnitski{at}Dal.Ca (A.M.); Kenneth.Rockwood{at}Dal.Ca (K.R.)

http://sageke.sciencemag.org/cgi/content/full/sageke;2003/12/vp2

Key Words: aging • fitness • frailty • integrative approach • macroscopic state variable • mathematical modeling

Abstract: In "Help Wanted: Physiologists for Research on Aging," George Martin challenged the scientific community to find better means of tackling aging of the whole organism. Although initiatives such as those proposed by Martin would be most welcome, we propose an additional means by which scientists can take into account the integrative response of the organism and its changes over time. This method consists of systematizing facts that cannot necessarily be explained by considering those facts in isolation.

Citation: A. Mitnitski, K. Rockwood, Help Available--Phenomenological Models for Research on Aging. Sci. SAGE KE 2003, vp2 (26 March 2003)
http://sageke.sciencemag.org/cgi/content/full/sageke;2003/12/vp2

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Science of Aging Knowledge Environment. ISSN 1539-6150