Sci. Aging Knowl. Environ., 25 June 2003
Senescence in a Bacterium with Asymmetric Division
Martin Ackermann, Stephen C. Stearns, and Urs Jenalhttp://sageke.sciencemag.org/cgi/content/abstract/sageke;2003/25/or8
Abstract: Science 300, 1920 (2003).
Senescence is a deterioration of function with age manifested as a decrease in reproduction and survival. Prokaryotes are considered to be nonsenescent and potentially immortal organisms. In this Brevia, Ackermann et al. show that an asymmetrically dividing bacterium, Caulobacter crescentus, exhibits a decrease in reproductive output with age. This organism may be used as a model system for studies of the fundamental properties of senescence.
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