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Sci. Aging Knowl. Environ., 23 July 2003
Vol. 2003, Issue 29, p. or13

OTHER RESOURCES

Drug Deals Diabetes a One-Two Punch

Jennifer Couzin

http://sageke.sciencemag.org/cgi/content/abstract/sageke;2003/29/or13

Abstract: Science 301, 290 (2003).

An enzyme called glucokinase regulates two key functions that fail in diabetics: secretion of insulin by the pancreas and production of glucose by the liver. A news story on page 290 of the 18 July 2003 issue of Science discusses a report of a glucokinase activator that caused blood sugar levels in diabetic mice to plummet by half.

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