Sci. Aging Knowl. Environ., 13 August 2003
Vol. 2003, Issue 32, p. tr2
[DOI: 10.1126/sageke.2003.32.tr2]

TEACHING RESOURCES

Estrogen, Bone, and Osteoporosis

B. Lawrence Riggs

Mayo Clinic, Rochester, MN 55905, U.S.A. E-mail: riggs.lawrence{at}mayo.edu

http://sageke.sciencemag.org/cgi/content/abstract/sageke;2003/32/tr2

Key Words: estrogen receptor • testosterone • paracrine cytokines • osteoclast • osteoblast • RANK

Abstract: Until 1995, scientists held five widely accepted pillars of belief about estrogen action in the skeleton. Since then, a sea change in conventional wisdom has swept away these five beliefs. This lecture reviews data that have proved them wrong--or at least incomplete--and describes the new paradigms that have emerged to replace them.

[Presentation]

References

1. B. L. Riggs, S. Khosla, L. J. Melton III, Sex steroids and the construction and conservation of the adult skeleton. Endocr. Rev. 23, 279-302 (2003). [Abstract] [Full Text]

Citation: B. L. Riggs, Estrogen, Bone, and Osteoporosis. Sci. SAGE KE 2003 (32), tr2 (2003).








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