Sci. Aging Knowl. Environ., 27 August 2003
Vol. 2003, Issue 34, p. nf16
[DOI: 10.1126/sageke.2003.34.nf16]

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The Mouse That Roared

Andrzej Bartke began studying reproductive hormones in dwarf mice as a grad student. Thirty years later, his lab serendipitously discovered that the midget mice are long-lived

Ingfei Chen

http://sageke.sciencemag.org/cgi/content/full/sageke;2003/34/nf16

Abstract: Physiologist Andrzej Bartke, of Southern Illinois University School of Medicine in Springfield, made his official debut in biogerontology in 1996 with the discovery that the growth-hormone-deficient Ames dwarf mouse has an extended life span. At that time, Bartke already had 30 years of successes in endocrinology research under his belt, including work that elucidated the role of the hormone prolactin in male reproduction. Born in Poland, Bartke studied zoology at Krakow's Jagiellonian University and conducted research for a year in Vietnam before obtaining a Ph.D. from the University of Kansas, Lawrence. His interest in aging arose from endocrinology studies, done in the early 1990s, of giant mutant mice that overproduce growth hormone and seem to grow old prematurely. Since then Bartke has become a leading expert on the physiology of how growth hormone influences aging and life span.

Citation: I. Chen, The Mouse That Roared. Sci. SAGE KE 2003 (34), nf16 (2003).

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