Sci. Aging Knowl. Environ., 29 October 2003
Vol. 2003, Issue 43, p. nw147
[DOI: 10.1126/sageke.2003.43.nw147]

NOTEWORTHY ARTICLES

Guinness-Bound

Mutated, manipulated worms set nematode life-span record

Mary Beckman

http://sageke.sciencemag.org/cgi/content/full/sageke;2003/43/nw147

Key Words: daf-2(e1370)daf-2(e1368) • gonad ablation • class 1 mutants • class 2 mutants • dauer

Abstract: Living a long time means nothing without good health, and until now, the nematode worms with the greatest life spans have been sickly. Now, researchers have created extremely long-lived worms that are spry to boot. Neutering worms after slashing the amount of a particular protein makes them last six times longer than normal. The work suggests that animals don't have to give up good health to achieve remarkably long life.

Citation: M. Beckman, Guinness-Bound. Sci. SAGE KE 2003 (43), nw147 (2003).

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