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Science Signaling - Call for Papers

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Sci. Aging Knowl. Environ., 19 November 2003
Vol. 2003, Issue 46, p. nw159
[DOI: 10.1126/sageke.2003.46.nw159]

NOTEWORTHY ARTICLES

Whodunit?

Product of neuron-damaging enzyme cleared of wrongdoing

R. John Davenport

http://sageke.sciencemag.org/cgi/content/full/sageke;2003/46/nw159

Key Words: cerebral ischemia • superoxide dismutase • EP2 • EP3

Abstract: NEW ORLEANS, LOUISIANA--In a brain-cell murder mystery, a prime suspect has turned out to be a hero, according to work presented here 8 and 11 November 2003 at the Society for Neuroscience Annual Meeting. A molecule produced by an enzyme implicated in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases protects rather than harms neurons. The observation suggests possible new treatments for ALS, stroke, and other conditions that kill nerve cells.

Citation: R. J. Davenport, Whodunit? Sci. Aging Knowl. Environ. 2003 (46), nw159 (2003).

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