Sci. Aging Knowl. Environ., 10 December 2003
Vol. 2003, Issue 49, p. nw167
[DOI: 10.1126/sageke.2003.49.nw167]

NOTEWORTHY ARTICLES

Battle Scars

Cells in the elderly immune system remember old skirmishes but not recent ones

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/2003/49/nw167

Key Words: FACS analysis • TH1 • TH2 • IL-2

Abstract: Senior citizens who continually misplace their glasses can still recall childhood episodes in vivid detail. The immune system's "memory" seems to age similarly, according to new work. The study shows that immunological memories etched early in life persist, but those established in old age fade. The findings could explain why vaccines often are ineffective in older folks.

Citation: M. Leslie, Battle Scars. Sci. Aging Knowl. Environ. 2003 (49), nw167 (2003).

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