Sci. Aging Knowl. Environ., 12 February 2003
Vol. 2003, Issue 6, p. ns1
[DOI: 10.1126/sageke.2003.6.ns1]

NEWS SYNTHESIS

Stress for Success

Too much stress is bad, but the right amount can prolong life and bring other benefits

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/sageke;2003/6/ns1

Abstract: Researchers in aging and other fields are warming to hormesis, the idea that moderate doses of heat, toxicants, radiation, or other stresses are helpful. The notion fell into disrepute because of early supporters' belief in homeopathy, but a plethora of data supports it. Experts on aging are now trying to dissect the molecular pathways behind hormesis to find out how they increase life-span and bestow other benefits. The small amount investigators have learned suggests that hormesis might erect some of the same defenses as do life-extending mutations, such as increased amounts of heat shock proteins that prevent other proteins from unfolding. Further research might allow doctors to use hormesis to aid aging patients.

Citation: M. Leslie, Stress for Success. Sci. SAGE KE 2003 (6), ns1 (2003).

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