Sci. Aging Knowl. Environ., 7 January 2004
Vol. 2004, Issue 1, p. nf2
[DOI: 10.1126/sageke.2004.1.nf2]

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Picky Eater

Gluttonous cellular recycler hungers for damaged proteins

R. John Davenport

http://sageke.sciencemag.org/cgi/content/full/2004/1/nf2

Abstract: SAN FRANCISCO, CALIFORNIA--In a restaurant or a cell, a voracious eater can still have refined tastes. A cellular hog is even more discriminating than previously thought, according to work presented here 14 December at the American Society for Cell Biology annual meeting. The protein-digesting organelle known as the lysosome prefers oxidized molecules, according to the study. Because this cellular component loses its appetite with age, the new study suggests one way that marred proteins accumulate over time.

Citation: R. J. Davenport , Picky Eater. Sci. Aging Knowl. Environ. 2004 (1), nf2 (2004).

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