Sci. Aging Knowl. Environ., 7 January 2004
Conflicting results underscore questions about how calorie restriction activates yeast longevity enzyme
R. John Davenporthttp://sageke.sciencemag.org/cgi/content/full/2004/1/nf5
Abstract: Stemming sugar intake sparks a yeast longevity protein, and two new studies offer differing views of the mechanism. The data clash on whether cutting calories reduces amounts of a particular enzyme blocker. Resolving this issue could help clarify how metabolic changes induced by this diet lengthen life in yeast--and whether related changes might do the same in mammals.
Citation: R. J. Davenport, UnSIRtainty Principle. Sci. Aging Knowl. Environ. 2004 (1), nf5 (2004).
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