Sci. Aging Knowl. Environ., 10 March 2004
Vol. 2004, Issue 10, p. pe11
[DOI: 10.1126/sageke.2004.10.pe11]


Can the Clock Be Turned Back on Ovarian Aging?

Patricia B. Hoyer

Patricia B. Hoyer is in the Department of Physiology at the University of Arizona, Tucson, AZ 85721, USA. E-mail: hoyer{at}

Key Words: germ cells • oocyte • ovary • follicle • menopause • fertility

Abstract: A basic tenet of reproductive biology is that female mammals are born with a set number of germ cells (oocytes). A new study by Johnson et al. challenges these beliefs by demonstrating that the postnatal mouse ovary contains actively dividing germ cells. These findings have implications for prolonging the reproductive life span of women.

Citation: P. B. Hoyer, Can the Clock Be Turned Back on Ovarian Aging? Sci. Aging Knowl. Environ. 2004 (10), pe11 (2004).

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