Sci. Aging Knowl. Environ., 17 March 2004
Vol. 2004, Issue 11, p. nf30
[DOI: 10.1126/sageke.2004.11.nf30]

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Greasing the Way for Bone Growth

Signaling molecule steers cells toward bone and away from fat

R. John Davenport

http://sageke.sciencemag.org/cgi/content/full/2004/11/nf30

Abstract: BANFF, CANADA--Healthy bodies keep fat thin and bones thick, and new research presented here 5 March 2004 at the Adipogenesis and Obesity Keystone Symposium reveals one way to achieve that goal. A single molecule sparks a signaling pathway that encourages bone formation and curtails corpulence. The work suggests that defects in the molecule might underlie a metabolic transition that occurs during aging, perhaps pointing the way toward new bone-strengthening therapies.

Citation: R. J. Davenport, Greasing the Way for Bone Growth. Sci. Aging Knowl. Environ. 2004 (11), nf30 (2004).

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