Sci. Aging Knowl. Environ., 17 March 2004
Vol. 2004, Issue 11, p. nf31
[DOI: 10.1126/sageke.2004.11.nf31]

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Going Ku Ku on Bax

Extrachemical affair shatters union, provokes suicide

Mary Beckman

http://sageke.sciencemag.org/cgi/content/full/2004/11/nf31

Abstract: When dramatic machinations part Shakespearean lovers, the play usually comes to a tragic end. But when biological forces divide a pair of proteins in cancer-prone cells, the show goes on for the lucky organism. Now, researchers have discovered the molecular intrigue that keeps the curtain up: Troubled cells chemically modify a particular protein and free its partner, which incites suicide. The results suggest ways to improve cancer therapies.

Citation: M. Beckman, Going Ku Ku on Bax. Sci. Aging Knowl. Environ. 2004 (11), nf31 (2004).

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