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Sci. Aging Knowl. Environ., 24 March 2004
Vol. 2004, Issue 12, p. nf33
[DOI: 10.1126/sageke.2004.12.nf33]

NEWS FOCUS

The Little RNAs That Could

Midget RNA molecules trigger neuron maturation through unexpected mechanism

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/2004/12/nf33

Abstract: Like many teenagers, stem cells won't grow up without a push. New research reveals that RNA snippets provide a shove, inciting brain stem cells to mature. The work suggests that RNAs instigate the process by changing a gene-blocking protein into a gene activator. The study is the first to show that the miniature molecules can turn genes on as well as off.

Citation: M. Leslie, The Little RNAs That Could. Sci. Aging Knowl. Environ. 2004 (12), nf33 (2004).

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