Sci. Aging Knowl. Environ., 7 April 2004
More Without TOR
Inhibiting nutrient sensor extends life span in fruit flies
Abstract: Scarfing pizzas wouldn't shorten a person's life if the body didn't notice the extra intake. Similarly, flies can eat rich food and not die early if a nutrient-sensing gadget is turned down, according to a new study. Quelling a protein that detects an abundance of food delays fly death, the work shows. The result suggests a potential mechanistic connection between decreased insulin-like signaling and calorie restriction, two manipulations that increase life span.
Citation: M. Beckman, More Without TOR. Sci. Aging Knowl. Environ. 2004 (14), nf36 (2004).
Science of Aging Knowledge Environment. ISSN 1539-6150