Sci. Aging Knowl. Environ., 7 April 2004
Vol. 2004, Issue 14, p. nf37
[DOI: 10.1126/sageke.2004.14.nf37]


Composed by Leptin

Early in life, appetite hormone sets up circuitry that controls food intake during adulthood

Mary Beckman

Abstract: Like many bands remembered for one popular song, leptin has been thought of as a one-hit wonder for suppressing appetite in adults. Now, research shows that the hormone plays another tune: It orchestrates the routing of key circuits in developing mouse brains that it uses to suppress appetite later in life. The results reveal how appetite-regulating brain regions develop and might explain why low-birth-weight babies often grow up to be obese.

Citation: M. Beckman, Composed by Leptin. Sci. Aging Knowl. Environ. 2004 (14), nf37 (2004).

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