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Sci. Aging Knowl. Environ., 7 April 2004
Vol. 2004, Issue 14, p. nf38
[DOI: 10.1126/sageke.2004.14.nf38]

NEWS FOCUS

Hidden Talents

Proteins implicated in Alzheimer's disease also coddle brain cells

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/2004/14/nf38

Abstract: To stem the damage from Alzheimer's disease, researchers hope to slice the supply of {beta} amyloid, a protein that fouls the brains of AD patients. But new work suggests that eliminating two proteins that help make {beta} amyloid undermines long-term memory and incites brain deterioration. The finding raises questions about the safety of anti-AD drugs that curtail the production of {beta} amyloid.

Citation: M. Leslie, Hidden Talents. Sci. Aging Knowl. Environ. 2004 (14), nf38 (2004).

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