Sci. Aging Knowl. Environ., 14 April 2004
Vol. 2004, Issue 15, p. nf39
[DOI: 10.1126/sageke.2004.15.nf39]

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Puzzling Out the Pieces

Dieting and dwarfism work together and separately at the molecular level to boost longevity

Esther Landhuis

http://sageke.sciencemag.org/cgi/content/full/2004/15/nf39

Abstract: Solving a particular jigsaw puzzle from a mound of pieces poses a challenge, especially when the pieces are from multiple puzzles. Scientists face a similar hurdle when fitting together the mechanisms of two well-studied life-extending methods, given the huge number of molecules in an organism. Using gene-chip technology, they have now pulled out some probable key components. The work supports the notion that two life-extension pathways harness some of the same molecules, and it also focuses researchers on specific genes that participate in these pathways.

Citation: E. Landhuis, Puzzling Out the Pieces. Sci. Aging Knowl. Environ. 2004 (15), nf39 (2004).

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Science of Aging Knowledge Environment. ISSN 1539-6150