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Sci. Aging Knowl. Environ., 28 April 2004
Vol. 2004, Issue 17, p. pe17
[DOI: 10.1126/sageke.2004.17.pe17]


Methods for Genetic Dissection of Complex Traits

Trudy F. C. Mackay

The author is in the Department of Genetics, North Carolina State University, Raleigh, NC 27695, USA. E-mail: trudy_mackay{at}

Key Words: quantitative trait loci • genetics • Drosophila • allelic effects • epistasis • polymorphisms

Abstract: In this Perspective, the author responds to a recent SAGE KE Perspective. An alternative view of the benefits of quantitative trait loci mapping as a way to understand the molecular mechanisms of life-span determination is presented.

Citation: T. F. C. Mackay, Methods for Genetic Dissection of Complex Traits. Sci. Aging Knowl. Environ. 2004 (17), pe17 (2004).

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Science of Aging Knowledge Environment. ISSN 1539-6150