Sci. Aging Knowl. Environ., 5 May 2004
DNA-break repair pathway poops out in older cells
Abstract: Like students whose motivation level wanes as summer nears, a molecular crew that mends fractured DNA gets lazy toward the end of an animal's life, according to new work. The findings spotlight a pathway whose breakdown could explain how elderly genomes become riddled with errors, which boosts cancer risk.
Citation: E. Landhuis, Slacking Off. Sci. Aging Knowl. Environ. 2004 (18), nf46 (2004).
Science of Aging Knowledge Environment. ISSN 1539-6150