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Sci. Aging Knowl. Environ., 14 January 2004
Vol. 2004, Issue 2, p. nf8
[DOI: 10.1126/sageke.2004.2.nf8]

NEWS FOCUS

{beta} Amyloid's Accomplice?

Molecular hit man might help Alzheimer's protein take out brain's white matter

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/2004/2/nf8

Abstract: Alzheimer's disease (AD) decimates not only neurons, but also the white matter, the information-transmitting interior of the brain. A new study suggests that {beta} amyloid, the protein that accumulates in the brains of AD patients, incites this devastation by recruiting another molecule that provokes cell suicide. The results could help researchers craft ways to spare the brain in AD patients, although some experts are skeptical of the finding.

Citation: M. Leslie, {beta} Amyloid's Accomplice? Sci. Aging Knowl. Environ. 2004 (2), nf8 (2004).

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