Sci. Aging Knowl. Environ., 19 May 2004
Vol. 2004, Issue 20, p. nf51
[DOI: 10.1126/sageke.2004.20.nf51]


Anxious Aging

Oxidatively stressed and old flies turn on many similar genes

Mary Beckman

Abstract: People complain that getting old is stressful, and now scientists might have proven them right. Many of the same genes change their output in old flies and oxidatively stressed young flies, suggesting that the aged insects are beleaguered on the molecular level. In addition, an aging-related increase in the activity of immune-system genes supports the notion that a general inflammatory response heightens as animals age. The results also reveal bursts of protein production that might eventually allow scientists to predict an individual fly's life span.

Citation: M. Beckman, Anxious Aging. Sci. Aging Knowl. Environ. 2004 (20), nf51 (2004).

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