Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Sci. Aging Knowl. Environ., 7 July 2004
Vol. 2004, Issue 27, p. ns4
[DOI: 10.1126/sageke.2004.27.ns4]

NEWS SYNTHESIS

All Pain, No Gain

The immune system sags with age, and responsiveness to vaccines goes with it. As immunologists learn why immunity falters, they might soon be able to give shots more punch

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/2004/27/ns4

Abstract: Along with their strength and teeth, the elderly typically lose their responsiveness to vaccines. Researchers are uncovering what goes wrong as we age, knowledge that might allow them to tailor vaccines for older folks or pep up the aging immune system. One failing is the disappearance of the thymus, the gland in which T cells mature. The blood also fills with inert T cells lacking a key surface molecule. These cells might accumulate because of infection with microbes that can lurk in the body for decades. Although researchers can't yet rejuvenate the immune system, they are exploring options from reformulating vaccines to removing troublesome T cells from the blood.

Citation: M. Leslie, All Pain, No Gain. Sci. Aging Knowl. Environ. 2004 (27), ns4 (2004).

Read the Full Text







To Advertise     Find Products


Science of Aging Knowledge Environment. ISSN 1539-6150