Sci. Aging Knowl. Environ., 14 July 2004
Vol. 2004, Issue 28, p. nf65
[DOI: 10.1126/sageke.2004.28.nf65]


Opposites Detract

Hunger hormone quenches inflammation, opposing leptin

Mitch Leslie

Abstract: Sherlock Holmes had Professor Moriarty. Magic Johnson had Larry Bird. Britney Spears has Christina Aguilera. A less famous rivalry occurs in the body, pitting the weight-regulating hormones leptin and ghrelin against each other. The molecules not only exert opposite effects on appetite, but new research suggests that they trigger contrasting reactions from the immune system. The discovery might help researchers develop treatments that soothe diseases that can stem from inflammation, including diabetes and atherosclerosis.

Citation: M. Leslie, Opposites Detract. Sci. Aging Knowl. Environ. 2004 (28), nf65 (2004).

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