Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Sci. Aging Knowl. Environ., 29 September 2004
Vol. 2004, Issue 39, p. nf89
[DOI: 10.1126/sageke.2004.39.nf89]


Knife Jugglers

Painkillers shift Alzheimer's protein slicer

R. John Davenport

Abstract: A small slip at the cutting board can mean the difference between beautifully diced vegetables and a severed finger. An even more subtle miss might explain how one class of painkillers reduces the risk of Alzheimer's disease (AD). According to new work, the drugs nudge a cellular butcher, prodding it to dice a protein into a harmless form rather than one that clumps in the brains of AD patients. The study reveals how the painkillers alter the protein chopper and might provide a new method for identifying potential AD drugs.

Citation: R. J. Davenport, Knife Jugglers. Sci. Aging Knowl. Environ. 2004 (39), nf89 (2004).

Read the Full Text

To Advertise     Find Products

Science of Aging Knowledge Environment. ISSN 1539-6150