Sci. Aging Knowl. Environ., 20 October 2004
Vol. 2004, Issue 42, p. nf95
[DOI: 10.1126/sageke.2004.42.nf95]


Gone to Waste

Inflammation-producing compound spurs muscle deterioration

Mitch Leslie

Abstract: Like a strait-laced businessman cutting loose in Las Vegas, an inflammation-controlling molecule behaves uncharacteristically in a certain milieu. New work suggests that the protein spurs muscle weakness not by prodding inflammation but by directing cells to destroy their own proteins. The work might shed light on how aging undermines strength and could lead to treatments for some types of muscle degradation that are common in the elderly.

Citation: M. Leslie, Gone to Waste. Sci. Aging Knowl. Environ. 2004 (42), nf95 (2004).

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