Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Subscribe

Sci. Aging Knowl. Environ., 27 October 2004
Vol. 2004, Issue 43, p. ns8
[DOI: 10.1126/sageke.2004.43.ns8]

NEWS SYNTHESIS

The Goldilocks Genes

Our chromosomes can get sloppy and delete or pick up genes. Researchers are starting to probe how these DNA miscues affect health and longevity

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/2004/43/ns8

Abstract: From cancer biologists to geneticists, scientists are tackling the question of how raising or lowering the number of gene copies from the standard two affects how we live and how soon we die. New genomic studies show that large-scale DNA duplications and deletions are more common than scientists imagined, even in healthy people. Other work demonstrates that our supply of gene copies matters in Parkinson's disease and cancer. The results raise the possibility that how fast we age depends in part on how many duplicates of certain genes we carry.

Citation: M. Leslie, The Goldilocks Genes. Sci. Aging Knowl. Environ. 2004 (43), ns8 (2004).

Read the Full Text

To Advertise     Find Products

Science of Aging Knowledge Environment. ISSN 1539-6150