Sci. Aging Knowl. Environ., 17 November 2004
Ironing Out Cell Death
Metal-grabbing enzyme saves suicidal cells
Abstract: Like a governor giving a pardon, the molecule NF-B spares cells condemned to death. New research reveals that the protein delivers its stay of execution by enlisting an iron-absorbing protein, which short-circuits a death-promoting pathway. The work could help researchers devise better treatments for conditions in which cells ignore suicide directives, including cancer and rheumatoid arthritis.
Citation: M. Leslie, Ironing Out Cell Death. Sci. Aging Knowl. Environ. 2004 (46), nf102 (2004).
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