Sci. Aging Knowl. Environ., 24 November 2004
Vol. 2004, Issue 47, p. nf104
[DOI: 10.1126/sageke.2004.47.nf104]


Heads and Tails

Less-active tumor suppressor paradoxically promotes both longevity and cancer in humans

Mary Beckman

Abstract: Like a coin, the p53 protein has two sides. It lengthens human life span but more than doubles the likelihood of death by cancer, new research shows. The observation supports the notion that animals give up extra years in order to be free of malignancies.

Citation: M. Beckman, Heads and Tails. Sci. Aging Knowl. Environ. 2004 (47), nf104 (2004).

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