Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Applied Biosytems - Introducing Silencer Select siRNAs

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Sci. Aging Knowl. Environ., 4 February 2004
Vol. 2004, Issue 5, p. nf15
[DOI: 10.1126/sageke.2004.5.nf15]

NEWS FOCUS

Tugging at Heartstrings

Protein associated with heart abnormalities and premature aging syndrome transmits mechanical stress to the nucleus

R. John Davenport

http://sageke.sciencemag.org/cgi/content/full/2004/5/nf15

Abstract: A runner needs resilient tendons to move joints and withstand impact. Similarly, a cell needs molecular rubber bands to remain supple. A protein whose defective forms trigger several human diseases, including a premature aging syndrome, normally helps cells respond to mechanical stress, according to new studies in mice. The work provides the strongest evidence yet for how alterations in the protein stir up trouble.

Citation: R. J. Davenport, Tugging at Heartstrings. Sci. Aging Knowl. Environ. 2004 (5), nf15 (2004).

Read the Full Text

ADVERTISEMENT
Click Me!

ADVERTISEMENT
Click Me!

To Advertise     Find Products