Sci. Aging Knowl. Environ., 5 January 2005
Vol. 2005, Issue 1, p. nf2
[DOI: 10.1126/sageke.2005.1.nf2]


Mix and Mismatch

Cancer-promoting protein introduces mistakes in DNA pairing

Mitch Leslie

Abstract: DNA is as predictable as a bad sitcom--adenine lines up opposite thymine, and cytosine faces guanine. But occasionally nucleotides don't pair correctly, a flaw that can lead to cancer. A protein implicated in some tumors disrupts cells' ability to fix these errors, according to a new study. The work reveals a new function for the protein and might allow doctors to refine cancer treatments.

Citation: M. Leslie, Mix and Mismatch. Sci. Aging Knowl. Environ. 2005 (1), nf2 (2005).

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Science of Aging Knowledge Environment. ISSN 1539-6150