Sci. Aging Knowl. Environ., 16 March 2005
How Low Can You Go?
Molecule might improve statins' cholesterol-depleting power
R. John Davenporthttp://sageke.sciencemag.org/cgi/content/full/2005/11/nf20
Abstract: Efforts to lower cholesterol can backfire, but new work suggests a route for attaining that goal. Cholesterol-abating drugs spur production of an enzyme that helps manufacture the fatty compound, undermining their effectiveness. The results suggest that a cholesterol-like molecule helps eliminate the enzyme. Tapping into this mechanism might aid efforts to improve the drugs.
Citation: R. J. Davenport, How Low Can You Go? Sci. Aging Knowl. Environ. 2005 (11), nf20 (2005).
Science of Aging Knowledge Environment. ISSN 1539-6150