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Sci. Aging Knowl. Environ., 16 March 2005
Vol. 2005, Issue 11, p. nf20
[DOI: 10.1126/sageke.2005.11.nf20]

NEWS FOCUS

How Low Can You Go?

Molecule might improve statins' cholesterol-depleting power

R. John Davenport

http://sageke.sciencemag.org/cgi/content/full/2005/11/nf20

Abstract: Efforts to lower cholesterol can backfire, but new work suggests a route for attaining that goal. Cholesterol-abating drugs spur production of an enzyme that helps manufacture the fatty compound, undermining their effectiveness. The results suggest that a cholesterol-like molecule helps eliminate the enzyme. Tapping into this mechanism might aid efforts to improve the drugs.

Citation: R. J. Davenport, How Low Can You Go? Sci. Aging Knowl. Environ. 2005 (11), nf20 (2005).

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Science of Aging Knowledge Environment. ISSN 1539-6150