Sci. Aging Knowl. Environ., 30 March 2005
Mopping Up Nuclear Waste
Molecule helps dispose of damaged proteins in the cell's command center
Abstract: A cell relies on molecular janitors to clear away trashed proteins, but researchers didn't know whether these cleanup crews tidied the nucleus. However, a new study identifies a housekeeping molecule that works in that structure, dispatching damaged proteins to the cell's refuse incinerator. The molecule may play a role in illnesses that involve protein buildup in the nucleus, such as Parkinson's disease.
Citation: M. Leslie, Mopping Up Nuclear Waste. Sci. Aging Knowl. Environ. 2005 (13), nf25 (2005).
Science of Aging Knowledge Environment. ISSN 1539-6150