Sci. Aging Knowl. Environ., 6 April 2005
Vol. 2005, Issue 14, p. nf27
[DOI: 10.1126/sageke.2005.14.nf27]

NEWS FOCUS

Giant Steps

Under tension, massive muscle protein relays signal to nucleus

R. John Davenport

http://sageke.sciencemag.org/cgi/content/full/2005/14/nf27

Abstract: It's a stretch to connect muscle fibers and genes, a new study suggests. Working muscles activate genes when they elongate a giant protein within their cells, the work reveals. Faults in the system underlie a rare muscle disease, but glitches might also contribute to weakness in the elderly.

Citation: R. J. Davenport, Giant Steps. Sci. Aging Knowl. Environ. 2005 (14), nf27 (2005).

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