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Sci. Aging Knowl. Environ., 11 May 2005 PERSPECTIVESKeep Time, Stay HealthyGene Block The author is in the Department of Biology at the University of Virginia, Charlottesville, VA 22903, USA. E-mail: gdb{at}virginia.edu http://sageke.sciencemag.org/cgi/content/full/2005/19/pe13Key Words: clock circadian rhythm obesity metabolic syndrome sleep-wake cycle
Abstract: Recent studies reveal that sleep loss in humans leads to metabolic disorders. A new study reports the development of metabolic syndrome in mice with altered circadian timing brought about by a mutation in a gene that functions in the biological clock. An intriguing and unanswered question is the relation between a healthy biological clock and normal appetite and weight regulation. Citation: G. Block, Keep Time, Stay Healthy. Sci. Aging Knowl. Environ. 2005 (19), pe13 (2005).
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Science of Aging Knowledge Environment. ISSN 1539-6150