Sci. Aging Knowl. Environ., 6 July 2005
Out-of-shape proteins speed death in neuron-destroying disease
Abstract: A squirming 5-year-old is annoying, but proteins that can't settle down might be lethal, according to new work. The study suggests that unstable versions of an oxidation-battling enzyme spark the fatal nerve disorder amyotrophic lateral sclerosis. The work supports preliminary studies that used molecular guardians to keep the protein in line.
Citation: M. Leslie, Odd SOD. Sci. Aging Knowl. Environ. 2005 (27), nf53 (2005).
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