Sci. Aging Knowl. Environ., 6 July 2005
Vol. 2005, Issue 27, p. pe21
[DOI: 10.1126/sageke.2005.27.pe21]

PERSPECTIVES

T-CIA: Investigating T Cells in Aging

Sven Koch, Juergen Kempf, and Graham Pawelec

The authors are at the Center for Medical Research at the University of Tuebingen, D-72072 Tuebingen, Germany. E-mail: graham.pawelec{at}uni-tuebingen.de (G.P.)

http://sageke.sciencemag.org/cgi/content/full/2005/27/pe21

Key Words: adaptive immunity • T cells • immunosenescence • biomarkers • immune risk profile

Abstract: Over the past few decades it has become clear that the immune system and especially T cells are instrumental in achieving a long and healthy life. The European Union (EU) previously supported several pan-European research projects coordinated from Tuebingen, Germany, aimed at providing a better understanding of immunosenescence. For 3 years, until the end of 2005, the EU is supporting a project called T cells in aging (T-CIA). The aim of T-CIA is to spy out and combine current efforts in immunology, molecular biology, and gerontology for a better understanding of why the elderly often have dysregulated immune responses and are more susceptible to infections and cancer.

Citation: S. Koch, J. Kempf, G. Pawelec, T-CIA: Investigating T Cells in Aging. Sci. Aging Knowl. Environ. 2005 (27), pe21 (2005).

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