Sci. Aging Knowl. Environ., 3 August 2005
Not a Chip off the Old Block
Study identifies unexpected function for mammalian version of yeast longevity protein
Abstract: Like a headstrong teen who refuses to enter the family accounting business and joins a rock band instead, the mammalian protein SIRT1 breaks with its relatives, according to a new study. SIRT1's kin in yeast promotes cell division, but the protein prods mouse cells to abandon reproduction. The work reveals SIRT1's previously unknown role in handling long-lasting stress.
Citation: M. Leslie, Not a Chip off the Old Block. Sci. Aging Knowl. Environ. 2005 (31), nf61 (2005).
Science of Aging Knowledge Environment. ISSN 1539-6150