Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Sci. Aging Knowl. Environ., 3 August 2005
Vol. 2005, Issue 31, p. nf62
[DOI: 10.1126/sageke.2005.31.nf62]


Detour to Death

Protein kills cells by diverting electrons and crafting free radicals

R. John Davenport

Abstract: Construction signs steer traffic around trouble, but new work reveals a diversion that routes cells into danger. A protein named p66Shc funnels electrons down an unusual path and uses them to make cell-killing compounds instead of energy. The results might help researchers understand why mice without the protein survive unusually well.

Citation: R. J. Davenport, Detour to Death. Sci. Aging Knowl. Environ. 2005 (31), nf62 (2005).

Read the Full Text

To Advertise     Find Products

Science of Aging Knowledge Environment. ISSN 1539-6150